Ataxia Global Initiative cordially invites you to the next Ataxia Global Conference:
Best endpoints: an evidence-based analysis and consensus suggestion for the currently best endpoints in each ataxia trial outcome domain.
It will take place online on 15 and 16 November 2023.
Registration
The registration is now open: register here. After the registration, you will receive the link to the meeting and a possibility to add the meeting to your calendar (recommended).
Industry registration fee: 490 €. No fee for academic and patient (organization) participants (not industry - academia, clinic, PAOs, etc.).
Description
During the conference, the AGI working Groups will present their work on best endpoints in their ataxia trial outcome domain. An endpoint is a defined parameter intended to reflect an outcome of interest that is statistically analyzed to address a particular research question (BEST 2016). The definition of endpoints is therefore of a special interest for clinical trials.
The work on best points will be presented for the patient-reported outcome, digital-motor gait and balance measures, NfL and MRI domains with a special interest in the patient meaningfulness and include consensus suggestion on the best endpoint in each domain. The endpoints will be presented for different aspects of a trial scenario with partial application for disease-modifying drug development.
Program
Wed., 15 November 2023, 12 – 2:45 pm CET
12:00 – 12:15 pm CET: Best Endpoints – developing an AGI Perspective
12:15 – 1:15 pm CET: Digital-Motor Gait/Balance Measures
15 min break
1:30 – 2:30 pm CET: Patient-Reported Ataxia Outcomes
2:30 – 2:45 pm CET: Wrap Up
Thurs., 16 November 2023, 8 pm – 10:35 pm CET
8 pm – 8:05 pm CET: Best Endpoints – interim update
8:05 – 9:05 pm CET: MRI
15 min break
9:20 – 10:20 pm CET: NfL
10:20 – 10:35 pm CET: Wrap Up