Ataxia Global Initiative has developed a new webinar series focused on preventive trials in the spinocerebellar ataxias (SCAs). Preventive approaches are the next logical step in ataxia research, building on advances in understanding pre-ataxic disease stages and early biomarkers. This concept has already been successfully explored in other neurodegenerative diseases, and the series aims to transfer these insights to SCAs. The program covers the rationale for preventive trials, lessons learned from related conditions, characterization of the pre-ataxic stage across different cohorts, and the potential of emerging biomarkers such as neurofilament light and MRI measures.
You can register for the series here:
REGISTRATION AT EVEENO
Webinar 1
Introduction. The Pre-Ataxic Stage of SCA3: ESMI Data
23 October 2025, 4-5 pm CEST
Speakers: Thomas Klockgether (Bonn, Germany), Jennifer Faber (Bonn, Germany)
Webinar 2
The Pre-Ataxic Stage of SCA2: Cuban Data
11 November 2025, 5-6 pm CEST
Speaker: Roberto Rodriguez-Labrada (Holguin, Cuba)
Webinar 3
The Pre-Ataxic Stage of SCA3: BIGPRO Data
2 December 2025, 5-6 pm CEST
Speaker: Laura Jardim (Porto Allegre, Brazil), tbc
Webinar 4
The Pre-Ataxic Stage of SCA7
13 January 2026, 4:30-5:30 pm CEST
Speaker: Giulia Coarelli (Paris, France)
Webinar 5
ATLAS Trial in ALS with a Focus on NfL
3 February 2026, 4-5 pm CEST
Speaker: tbc
Webinar 6
Potential of Digital Motor Measures as Biomarkers in Preventive Trials
24 February 2026, 4-5 pm CEST
Speaker: Winfried Ilg (Tübingen, Germany)
Webinar 7
Potential of MRI Measures as Biomarkers in Preventive Trials
10 March 2026, 4-5 pm CEST
Speaker: Gulin Oz (Minneapolis, MN, USA)
Webinar 8
Consideration on Preventive Trials in HD
24 March 2026, 5-6 pm CEST
Speaker: Sarah Tabrizi (London, UK)
Webinar 9
Preventive Trials in Autosomal Dominant AD: The DIAN-TU Experience
14 April 2026, 4-5 pm CEST
Speaker: Johannes Levin (Munich, Germany)
Webinar 10
Preventive Trials in SMA
5 May 2026, 4-5 pm CEST
Speaker: tbc
Final Session:
Design of Preventive Trials in SCAs
09 June 2026, 4-5 pm CEST
Speakers: Sophie Tezenas du Montcel (Paris, France), NN